{"id":11289,"date":"2021-12-05T20:00:00","date_gmt":"2021-12-06T03:00:00","guid":{"rendered":"https:\/\/gemstatepatriot.com\/blog\/?p=11289"},"modified":"2024-09-23T23:21:43","modified_gmt":"2024-09-24T05:21:43","slug":"covid-19-vaccine-engineered-synthesized","status":"publish","type":"post","link":"https:\/\/gemstatepatriot.com\/blog\/covid-19-vaccine-engineered-synthesized\/","title":{"rendered":"Covid-19 Vaccine: Engineered &#038; Synthesized"},"content":{"rendered":"\n<p>Vaccine technology has dramatically shifted from the <a href=\"https:\/\/www.historyofvaccines.org\/content\/articles\/different-types-vaccines\" target=\"_blank\" rel=\"noreferrer noopener\">manipulation<\/a> of a virus to foster immunity, to now what is called gene <a href=\"https:\/\/academic.oup.com\/intimm\/article\/33\/10\/521\/6194108\" target=\"_blank\" rel=\"noreferrer noopener\">therapy<\/a>. Much concern has been expressed about this new technology, does it change one&#8217;s genetic code, what are the long term effects given no long term studies have been done, and since a vaccinated individual can become infected with Covid-19, what is the purpose of getting one? Even though this is new technology we are assured it is <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0169409X20302933?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">safe<\/a> and can be given <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5906799\/\" target=\"_blank\" rel=\"noreferrer noopener\">repeatedly<\/a>. Are technocrats and scientists just messing with God&#8217;s creation of humans?<\/p>\n\n\n\n<p>While there are <a href=\"https:\/\/www.webmd.com\/lung\/news\/20210719\/covid-19-vaccines-not-gene-therapy\" target=\"_blank\" rel=\"noreferrer noopener\">claims<\/a> that the Covid-19 vaccine is not gene therapy, in looking at the scientific <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33772572\/\" target=\"_blank\" rel=\"noreferrer noopener\">literature<\/a> it is described as just that. Even this <a href=\"https:\/\/www.webmd.com\/lung\/news\/20210719\/covid-19-vaccines-not-gene-therapy\" target=\"_blank\" rel=\"noreferrer noopener\">article<\/a> describes one vaccine as using &#8220;double-stranded <a href=\"https:\/\/www.webmd.com\/a-to-z-guides\/dna-fingerprinting-overview\">DNA<\/a> inserted into a common, but inert virus called an adenovirus. This DNA also contains the instructions for building the spike protein. Once inside the cell, these instructions are read and translated into mRNA (messenger RNA).&#8221; It goes on, &#8220;The mRNA chains are basically work orders that spell out the instructions for making the spike proteins that stud the outside of the <a href=\"https:\/\/www.webmd.com\/lung\/coronavirus\">coronavirus<\/a> that causes COVID-19.&#8221; Ok, both genetic <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7789827\/\" target=\"_blank\" rel=\"noreferrer noopener\">materials<\/a>, DNA and mRNA, are being used. In the case of one Covid-19 vaccine, the spike <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8326314\/\" target=\"_blank\" rel=\"noreferrer noopener\">protein<\/a> of the Covid-19 virus is used to <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8538930\/\" target=\"_blank\" rel=\"noreferrer noopener\">drive<\/a> &#8220;into the host cell the genetic information needed to express the recombinant <a href=\"https:\/\/www.merriam-webster.com\/dictionary\/antigen\" target=\"_blank\" rel=\"noreferrer noopener\">antigen<\/a>&#8221; which evokes an immune response. It just leaves out one detail, that mRNA genetic material is <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27236789\/\" target=\"_blank\" rel=\"noreferrer noopener\">synthetic<\/a>.<\/p>\n\n\n\n<p>Being a highly technical and very complicated process, most of the nuances are not discussed here. The focus will be just on the issue of this vaccine actually being an <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33001626\/\">engineered<\/a> and synthetically produced product. Links to the scientific information discussing this are provided for those who want to do a deeper dive.<\/p>\n\n\n\n<p>Historically, it takes years to <a href=\"https:\/\/www.fda.gov\/vaccines-blood-biologics\/development-approval-process-cber\/vaccine-development-101\" target=\"_blank\" rel=\"noreferrer noopener\">create<\/a> a vaccine with many stages in the process. In the case of the Covid-19 <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8071766\/\" target=\"_blank\" rel=\"noreferrer noopener\">vaccine<\/a> it took less than one year. The virus is inactivated or weakened in traditional vaccines, and is called an <a href=\"https:\/\/www.merriam-webster.com\/dictionary\/antigen\" target=\"_blank\" rel=\"noreferrer noopener\">antigen<\/a> because it evokes an immune response. However, the Covid-19 mRNA vaccine is a Nucleic acid <a href=\"https:\/\/academic.oup.com\/intimm\/article\/33\/10\/521\/6194108\" target=\"_blank\" rel=\"noreferrer noopener\">vaccine<\/a> where a strand of a corona virus DNA is used to make a template that is engineered for the mRNA, which does the same, evokes an immune response.&nbsp;<\/p>\n\n\n\n<p>The complete process in this is far more <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7293463\/\" target=\"_blank\" rel=\"noreferrer noopener\">complicated<\/a> than what is explained here but through an engineering technique called a <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33514944\/\" target=\"_blank\" rel=\"noreferrer noopener\">reverse<\/a> genetic system, it is &#8220;<a href=\"https:\/\/www.news-medical.net\/health\/What-is-Reverse-Genetics.aspx\" target=\"_blank\" rel=\"noreferrer noopener\">genetically<\/a> engineering specific <a href=\"https:\/\/www.news-medical.net\/life-sciences\/What-is-Nucleic-Acid.aspx\">nucleic acid<\/a> sequences (within DNA or RNA).&#8221; More simply, a DNA sequence from a Covid-19 virus strand is used. DNA sequence information is readily available to technocrats through <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genbank\/\" target=\"_blank\" rel=\"noreferrer noopener\">GenBank<\/a> among many <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28573592\/\" target=\"_blank\" rel=\"noreferrer noopener\">other<\/a> available genome data <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/\" target=\"_blank\" rel=\"noreferrer noopener\">sources<\/a>. As of May, 2020 &#8220;more than 200 complete and partial genome sequences of SARS-CoV-2&#8221; were <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7218962\/\" target=\"_blank\" rel=\"noreferrer noopener\">decoded<\/a> and deposited in the Global Initiative on Sharing All Influenza <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5388101\/\" target=\"_blank\" rel=\"noreferrer noopener\">Data<\/a>. Scientists can easily pick and choose from these sources for vaccine experimentation.<\/p>\n\n\n\n<p>Through a process called In vitro transcription (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30067354\/\" target=\"_blank\" rel=\"noreferrer noopener\">IVT<\/a>), encoded information in the spike protein DNA is <a href=\"https:\/\/www.youtube.com\/watch?v=JQIwwJqF5D0\" target=\"_blank\" rel=\"noreferrer noopener\">taken<\/a> and encoded into mRNA, synthetically creating the spike protein, which produces the viral antigen. Using <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30067354\/\" target=\"_blank\" rel=\"noreferrer noopener\">IVT<\/a> to make the genetic copy for a Nucleic acid <a href=\"https:\/\/academic.oup.com\/intimm\/article\/33\/10\/521\/6194108\" target=\"_blank\" rel=\"noreferrer noopener\">vaccine<\/a>, mRNA &#8220;can be <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30067354\/\" target=\"_blank\" rel=\"noreferrer noopener\">manufactured<\/a> rapidly at large scale&#8221; using a &#8220;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33572452\/\" target=\"_blank\" rel=\"noreferrer noopener\">synthetic<\/a> mRNA format&#8221;. &#8220;Synthetic mRNA&#8221; vaccines are <a href=\"https:\/\/www.mdpi.com\/1999-4915\/13\/2\/270\/htm\" target=\"_blank\" rel=\"noreferrer noopener\">considered<\/a> &#8220;safer&#8221; than the more traditional attenuated virus vaccines while even claiming it will &#8220;bring a halt to the coronavirus pandemic.&#8221; Because it is synthetic it is easy to <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8071766\/\" target=\"_blank\" rel=\"noreferrer noopener\">design<\/a>, and can be manufactured at great speed for vaccine development.<\/p>\n\n\n\n<p>In these <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33514944\/\" target=\"_blank\" rel=\"noreferrer noopener\">engineered<\/a> vaccines the SARS-CoV-2 S <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8326314\/\" target=\"_blank\" rel=\"noreferrer noopener\">protein<\/a>, called the &#8220;spike protein&#8221; and found in corona <a href=\"https:\/\/en.wikipedia.org\/wiki\/Coronavirus_spike_protein\" target=\"_blank\" rel=\"noreferrer noopener\">viruses<\/a>, is targeted as the one which causes Covid-19. It &#8220;is an important target site for neutralizing antibodies and a <em>key target for vaccine <\/em><a href=\"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2021.36.e124\" target=\"_blank\" rel=\"noreferrer noopener\">design<\/a>.&#8221; 1286 amino <a href=\"https:\/\/socratic.org\/questions\/what-is-an-amino-acid-and-how-do-they-make-up-proteins\" target=\"_blank\" rel=\"noreferrer noopener\">acids<\/a> make up the spike protein <a href=\"https:\/\/www.prosci-inc.com\/ProductLeaflet\/file\/getpdf\/name\/SARS_CoV-2_full_length_spike_protein_in_DIBMA_Glycerol.pdf?fileId=125823\" target=\"_blank\" rel=\"noreferrer noopener\">sequence<\/a> while genomic <a href=\"https:\/\/nextstrain.org\/sars-cov-2\/\" target=\"_blank\" rel=\"noreferrer noopener\">data<\/a> of the virus is shared worldwide. This amino acid sequence was <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7789827\/\" target=\"_blank\" rel=\"noreferrer noopener\">aligned<\/a> with other coronavirus structural proteins, with concern about how this would work in future <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7151553\/\" target=\"_blank\" rel=\"noreferrer noopener\">mutations<\/a>.<\/p>\n\n\n\n<p>There continues to be controversy as to whether or not an actual Covid-19 virus has been isolated, however the SARS-CoV-2 proteins share high similarity to SARS-CoV and MERS-CoV which <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7749647\/\">contributed<\/a> to the development of SARS-CoV-2 vaccine design. Interestingly, through Covid-19 DNA protein manipulation several vaccines were tested.<\/p>\n\n\n\n<p>Once the DNA or RNA sequence of a virus is known it becomes a rapid way in which to engineer a synthetic vaccine. Being a messenger RNA, this engineered vaccine alerts our immune system to produce a specific antibody to the virus, just as the virus itself would do. Post injection the mRNA material itself hangs around long enough to evoke an immune response then disintegrates. By all reports this occurs within just a few days.<\/p>\n\n\n\n<p>These &#8220;computer-driven <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7151553\/\" target=\"_blank\" rel=\"noreferrer noopener\">strategies<\/a>&#8221; create &#8220;a synthetic vaccine&#8230;consisting mainly of synthetic peptides&#8221;. These vaccines produced by &#8220;chemical synthesis&#8221; are considered safer &#8220;because they do not involve cell-derived material or biological processes for production. Their purity can be controlled&#8221;. &#8220;Creating vaccines synthetically&#8230;has the ability to increase the speed of production and to <em>retune and fine tune the solution to combat new variations in pathogens.<\/em>&#8221; &#8220;Synthetic vaccines also have the advantage that they can be seen as cartridge vaccines, meaning that they contain bits and pieces that can readily be replaced by others to update the vaccine in order to combat new strains of pathogen.&#8221; In other words, DNA strands can easily be manipulated with different protein structures, an advantage to created vaccines for future mutations.<\/p>\n\n\n\n<p>Without going into the specifics on vectors, Johnson &amp; Johnson and Oxford-AstraZeneca are DNA\/Viral-vector <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8168329\/\" target=\"_blank\" rel=\"noreferrer noopener\">vaccines<\/a> which deliver the spike protein DNA material into the cells. Pfizer and Moderna are mRNA vaccines. The introduction of these genetic materials causes the cell to create the viral antigen. Regardless, both are gene therapy in that <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33514944\/\" target=\"_blank\" rel=\"noreferrer noopener\">engineered<\/a>, synthetic genetic viral material is introduced into the human cell to make the viral spike protein. This <a href=\"https:\/\/www.youtube.com\/watch?v=osRo-yz1VQ8\" target=\"_blank\" rel=\"noreferrer noopener\">video<\/a> is short, explains the immune system, traditional vaccines, and this new gene therapy. Rather than the virus injecting its RNA into a cell to make copies of it, through mRNA vaccines this viral process is replaced synthetically to create an immune response as explained in this <a href=\"https:\/\/www.youtube.com\/watch?v=WOvvyqJ-vwo\" target=\"_blank\" rel=\"noreferrer noopener\">video<\/a>. The synthetically created Covid-19 RNA is telling the cell genetically to produce the spike protein, clearly a form of gene <a href=\"https:\/\/medlineplus.gov\/genetics\/understanding\/therapy\/genetherapy\/\" target=\"_blank\" rel=\"noreferrer noopener\">therapy<\/a>.<\/p>\n\n\n\n<p>Up to this point, it is now understood that selected DNA from the virus is used to make <a href=\"https:\/\/www.mdpi.com\/1999-4915\/13\/2\/270\/htm\" target=\"_blank\" rel=\"noreferrer noopener\">synthetic<\/a> mRNA that is carried into the cell, evoking an immune response. But the beauty in all of this, since the viral genetic component can be picked over, copied, and manufactured, it is possible to &#8220;tweak&#8217; the genetic sequence in any new mutation. As a result, new vaccines can be made just as rapidly by altering the protein sequence to match the mutated variant. Regardless, these technocrats <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7472682\/\" target=\"_blank\" rel=\"noreferrer noopener\">conclude<\/a> that vaccine development will continue until more clinical trials are completed and that &#8220;the first round of vaccines will have waning immunity and require boosting using improved second-generation COVID-19 vaccines&#8221;&#8230;with those who have recovered from COVID-19 with poor or waning immunity may also require vaccination&#8221;.<\/p>\n\n\n\n<p>As the second concerning mutation has emerged, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8634699\/\" target=\"_blank\" rel=\"noreferrer noopener\">Omicron<\/a>, the reality is that there are &#8220;thousands of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8252702\/\" target=\"_blank\" rel=\"noreferrer noopener\">mutations<\/a>&#8221; that have accumulated. Even a local doctor <a href=\"https:\/\/idahonews.com\/news\/local\/local-doctor-on-covid-19-we-expect-this-virus-to-continue-to-mutate\" target=\"_blank\" rel=\"noreferrer noopener\">predicts<\/a> this virus will continue with mutations. Is this the cart before the horse or the other way around? Are these mRNA vaccines created because of the ability to manipulate them for any virus thus creating more experimentation and unending profit, or are the viruses being used to create more vaccines that come to the same end?&nbsp;<\/p>\n\n\n\n<p>The major pharmaceutical companies making these vaccines, <a href=\"https:\/\/www.weforum.org\/organizations\/pfizer\" target=\"_blank\" rel=\"noreferrer noopener\">Pfizer<\/a>, <a href=\"https:\/\/www.weforum.org\/organizations\/moderna-therapeutics\" target=\"_blank\" rel=\"noreferrer noopener\">Moderna<\/a>, and Johnson &amp; <a href=\"https:\/\/www.weforum.org\/organizations\/johnson-johnson\" target=\"_blank\" rel=\"noreferrer noopener\">Johnson<\/a> are all World Economic Forum (WEF) members. WEF is <a href=\"https:\/\/www.weforum.org\/agenda\/2021\/07\/everything-you-need-to-know-about-mrna-vaccines\/\" target=\"_blank\" rel=\"noreferrer noopener\">thrilled<\/a> to see this new technology as part of its 4th Industrial Revolution to change our healthcare but doesn&#8217;t see it replacing other vaccines, <a href=\"https:\/\/www.weforum.org\/agenda\/2021\/09\/why-mrna-wont-replace-other-vaccine-types-just-yet\/\" target=\"_blank\" rel=\"noreferrer noopener\">yet<\/a>, in its ongoing move towards <a href=\"https:\/\/www.weforum.org\/agenda\/2018\/01\/africa-lead-healthcare-fourth-industrial-revolution\/\" target=\"_blank\" rel=\"noreferrer noopener\">genomics<\/a>. After all, the &#8220;ability to <a href=\"https:\/\/www.weforum.org\/agenda\/2018\/11\/how-the-biological-century-will-transform-healthcare\/\" target=\"_blank\" rel=\"noreferrer noopener\">manipulate<\/a> genes is in its infancy.&#8221; As part of its corporatism plan, one could conjecture that someday the only option for vaccination provided to the masses will be these gene therapy experiments, whether wanted or not.<\/p>\n\n\n\n<p>As explained in the video in this WEF <a href=\"https:\/\/www.weforum.org\/agenda\/2021\/11\/synthetic-biology-can-benefit-all-expert-explains-how\/\" target=\"_blank\" rel=\"noreferrer noopener\">article<\/a> within the first ten minutes, synthetic <a href=\"https:\/\/www.technocracy.news\/wef-says-synthetic-biology-is-the-key-to-reset-living-systems\/\">biology<\/a>, which includes mRNA vaccines, is bringing together individuals with expertise in biology, engineering, computer science, social sciences, and humanities to collectively trying to<em> make biology easier to engineer, enabling the design and re-design of systems using the building blocks (DNA) of life<\/em>. It is also programming functions in DNA and using new engineering tools in learning to <em>engineer life<\/em>. And mRNA vaccines are part of that engineering. The WEF has put together a Global Future <a href=\"https:\/\/www.weforum.org\/communities\/gfc-on-synthetic-biology\" target=\"_blank\" rel=\"noreferrer noopener\">Council<\/a> on Synthetic Biology just for the purpose of engineering life. If it is too unbelievable, keep in mind it is currently being done through vaccines and will soon invade other aspects of life.<\/p>\n\n\n\n<p>Corporations are entering a dangerous area here, using humans and nature as lab rats, perhaps falsely believing help is on the way for mankind. As the old saying goes, It&#8217;s not nice to <a href=\"https:\/\/www.youtube.com\/watch?v=ijVijP-CDVI\" target=\"_blank\" rel=\"noreferrer noopener\">fool<\/a> Mother Nature, she is smarter than you think. As a society based on the foundation of Christian principles attention needs to be paid to the direction we are being taken, starting with these vaccines.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vaccine technology has dramatically shifted from the manipulation of a virus to foster immunity, to now what is called gene therapy. Much concern has been expressed about this new technology, does it change one&#8217;s genetic code, what are the long term effects given no long term studies have been done, and since a vaccinated individual [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":11290,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[962,1089,861],"class_list":["post-11289","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-covid-19","tag-vaccine-mandates","tag-vaccines","cat-1-id"],"_links":{"self":[{"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/posts\/11289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/comments?post=11289"}],"version-history":[{"count":1,"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/posts\/11289\/revisions"}],"predecessor-version":[{"id":11291,"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/posts\/11289\/revisions\/11291"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/media\/11290"}],"wp:attachment":[{"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/media?parent=11289"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/categories?post=11289"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gemstatepatriot.com\/blog\/wp-json\/wp\/v2\/tags?post=11289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}